Suppose that one of every 500 people in a certain population has a particular disease, which displays no symptoms. A blood test is available for screening for this disease. For a person who has this disease, the test always turns out positive. For a person who does not have the disease, however, there is a false positive rate--in other words, for such people, of the time the test will turn out negative, but of the time the test will turn out positive and will incorrectly indicate that the person has the disease. Let be the probability that a person who is chosen at random from this population and gets a positive test result actually has the disease. Which of the following is closest to ?
- A)
- B)
- C)
- D)
- E)
Answer
C
Key insight
Imagine 50,000 people: 100 are sick and test positive, but 2% of the 49,900 healthy people, 998 people, also test positive. So about 1 in 11 positives is real.
Solution
Probability questions like this are easiest if you imagine an actual crowd of people and count.
1. Pick a crowd size that makes the numbers whole. Take people.
2. One in every has the disease: sick people. They all test positive.
3. The other people are healthy. Of them, test positive by mistake: people.
4. So the people with a positive test are in all.
5. We want the chance that a person with a positive test is really sick. That is the sick positives out of all positives:
6. Compare with the choices: and . The value is closest to .
The answer is .
Why this works
The question only looks at people who tested positive and asks what fraction of them are sick. Healthy people far outnumber sick people, so even a small error rate among the healthy produces about ten times as many false alarms as real cases. Counting an imaginary crowd turns a confusing probability question into simple division.
Alternative approach
Use a crowd of instead. Exactly person is sick, and about healthy people test positive. Then , which is very close to .
The trap
Choosing 98/99 or 49/99 by mixing up 'a sick person tests positive' with 'a person who tests positive is sick', and ignoring how rare the disease is.
Concise solution
Imagine testing a group of people.
- Exactly person has the disease, and that person tests positive.
- The other are healthy, and of them test positive anyway: false positives.
So about people test positive, and only of them is actually sick:
Among the choices, is closest ( is noticeably farther).
The answer is .
Review in the AoPS books
- Introduction to Counting & Probability, Chapter 8: Basic Probability Techniques (§8.5)
- Introduction to Algebra, Chapter 6: Ratios and Percents
- Intermediate Counting & Probability, Chapter 11: Conditional Probability
- Introduction to Algebra, Chapter 7: Proportion (§7.1, §7.2, §7.3)
Techniques
Set up the equation/formula and compute; no special trick needed · Test small/specific values or special cases to find or verify the answer